The EDDDY-S study is an ongoing research project designed to find ways to help clinicians better assess risks in children and adolescents with type 1 diabetes.
Risk assessment, which includes identifying the stage to which the disease has progressed in the individual patient, is just as important in children and adolescents as it is in adults. If we can identify individuals who are at an increased risk of developing a specific complication, or who already show early signs of complications, action can be taken to address this, including the use of additional and/or more intensive treatment.
The EDDDY-S study is investigating new techniques for identifying early signs of micro- and macrovascular complications. Traditionally, surrogate endpoints and early signs of complications have included:
Newer endpoints and early signs include:
Sub-studies of EDDDY-S are addressing each of these newer endpoints/signs, with the aim of investigating their applicability in children and adolescents with type 1 diabetes, and if they can be usefully integrated along with older endpoints/signs into a more effective staging system for risk assessment.
Diabeter is ideally placed to conduct such research: the sub-study populations include patients attending our outpatient clinics, with the new tests and evaluations incorporated into the standard battery of assessments.