Improvement of Care & Outcome
In this study, Diabeter researchers assessed the prevalence of thyroid peroxidase autoimmunity (known to be associated with T1DM, although reported rates have varied from study to study) in a total of 1,553 patients younger than 25 years who were tested at the centre between 1993 and 2014.
A total of 4,591 measurements of antibody to thyroid peroxidase (ATPO) were made in that period, in 2,270 males (median age 14.1 years) and 2,321 females (median age 14.7 years). An ATPO value of 60 U/mL or higher was considered to be significantly elevated, as was a thyroid stimulating hormone (TSH) level above 4.4 mU/L.
Concluding, the researchers advocated “cost-effective screening in type 1 diabetes patients by ATPO measurements on a regular/annual basis, and to proceed in case of elevated ATPO values with close meshed TSH [thyroid-stimulating hormone] monitoring only”.