Projects

Improvement of Care & Outcome

The right diagnosis: is it type 1 or…?

T1DM has several clinical characteristics such as symptoms, age at onset, and limited genetic influence in families. However, studies show that around 3% of pediatric patients are misdiagnosed with T1DM. With the use of our disease management database system VCare, we are able to identify patients with non-type 1 factors such as low insulin dose, complex familial diabetes inheritance, and age at onset. We are developing a clinical diagnostic test to identify a possible need for a therapy change from insulin to oral drugs in patients with monogenetic diabetes. The use of genetic testing is also enabling us to identify new forms and new phenotypes of monogenetic diabetes.

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