We are continuing our efforts to develop simple yet robust techniques that can be applied in the clinic or at home to predict the risk of complications:

• Role of glucose variability
  By analysing continuous glucose measurement data, using our extensive VCare database, we will investigate the correlation between glucose fluctuations and the development of diabetic complications.
• New non-invasive measurements of vascular damage
  Early damage will be measured by new non-invasive techniques such as pulse-wave velocity, 24-hour blood pressure analysis, and heart-rate analysis.
• Biomarkers of damage: the role of microRNA fingerprints
  As part of the Biomarker project, we are collecting RNA samples to enable us to investigate the potential value of microRNA analysis.